Notice of Intent to Publish a Funding Opportunity Announcement for Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional)

Key Facts

Status: Open

Posted date: May 13, 2025

Opportunity ID: 358911

Opportunity number: NOT-DK-26-309

Opportunity category: Discretionary

Agency name: National Institutes of Health

Agency code: HHS-NIH11

Award floor: $0

Award ceiling: $1,835,051

Cost sharing required: No

Funding Instrument Types
  • Cooperative Agreement
Category of Funding Activity
  • Health
Eligible Applicants
  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_nih11
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:city_or_township_governments
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:nonprofits_that_do_not_have_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:special_district_governments
  • eligible_applicants:state_governments
  • funding_instrument_type:cooperative_agreement
  • opportunity_category:discretionary
  • status:open
Description

The National Institute of Diabetes and Digestive and Kidney Diseases, intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on liver cirrhosis. The Liver Cirrhosis Network has an ongoing clinical study, the Liver Cirrhosis Network Longitudinal Cohort Study; and an ongoing clinical trial, the Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (RESCU): A Double -Blind Randomized, Placebo-Controlled Phase 2 Study. The purpose of the intended limited competition renewal NOFO of RFA-DK-20-004 will be to complete the enrollment in both studies: Liver Cirrhosis Network Longitudinal Cohort Study; and the Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (RESCU): A Double -Blind Randomized, Placebo-Controlled Phase 2 Study. The Liver Cirrhosis Network Scientific and Data Coordination Center will provide clinical studies management and technical biostatistical assistance to perform data analyses; disseminate findings; and perform ancillary analyses. Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 cooperative agreement activity code. Investigators with expertise and insights into this area of liver disease are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in translational sciences will be encouraged and these investigators should also begin considering applying for this application.

Notice of Intent to Publish a Funding Opportunity Announcement for Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional)
The National Institute of Diabetes and Digestive and Kidney Diseases, intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on liver cirrhosis. The Liver Cirrhosis Network has an ongoing clinical study, the Liver Cirrhosis Network Longitudinal Cohort Study; and an ongoing clinical trial, the Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (RESCU): A Double -Blind Randomized, Placebo-Controlled Phase 2 Study. The purpose of the intended limited competition renewal NOFO of RFA-DK-20-004 will be to complete the enrollment in both studies: Liver Cirrhosis Network Longitudinal Cohort Study; and the Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (RESCU): A Double -Blind Randomized, Placebo-Controlled Phase 2 Study. The Liver Cirrhosis Network Scientific and Data Coordination Center will provide clinical studies management and technical biostatistical assistance to perform data analyses; disseminate findings; and perform ancillary analyses. Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 cooperative agreement activity code. Investigators with expertise and insights into this area of liver disease are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in translational sciences will be encouraged and these investigators should also begin considering applying for this application.
Notice of Intent to Publish a Funding Opportunity Announcement for Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional)
Open
National Institutes of Health
Health
Cooperative Agreement
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
2025-05-13