Single Source: Outcomes of Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network - Coordinating Center (U01 Clinical Trial Required)

Key Facts

Status: Open

Posted date: June 6, 2025

Opportunity ID: 359173

Opportunity number: FOR-HG-25-013

Opportunity category: Discretionary

Agency name: National Institutes of Health

Agency code: HHS-NIH11

Award floor: $0

Award ceiling: $0

Cost sharing required: No

Funding Instrument Types
  • Cooperative Agreement
Category of Funding Activity
  • Health
Eligible Applicants
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_nih11
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:others
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • funding_instrument_type:cooperative_agreement
  • opportunity_category:discretionary
  • status:open
Description

The National Human Genome Research Institute (NHGRI) intends to promote an initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit a sole-source application for a coordinating center to extend follow-up and collection of outcome data for the 25,000 participants receiving genomically informed risk assessment (GIRA) and management recommendations in the Electronic Medical Records and Genomics (eMERGE) Network. This multi-site continuation of the eMERGE Genomic Risk Assessment and Management Study will: 1) extend follow-up of eMERGE participants from a minimum 1 year to at least 4 years; 2) assess longer-term adherence to and outcomes of GIRA-based preventative recommendations among clinicians and participants; and 3) identify correlates of adherence by condition, participant age and demographics, and social determinants of health.This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2025. This NOFO will utilize the U01 activity code.

Single Source: Outcomes of Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network - Coordinating Center (U01 Clinical Trial Required)
The National Human Genome Research Institute (NHGRI) intends to promote an initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit a sole-source application for a coordinating center to extend follow-up and collection of outcome data for the 25,000 participants receiving genomically informed risk assessment (GIRA) and management recommendations in the Electronic Medical Records and Genomics (eMERGE) Network. This multi-site continuation of the eMERGE Genomic Risk Assessment and Management Study will: 1) extend follow-up of eMERGE participants from a minimum 1 year to at least 4 years; 2) assess longer-term adherence to and outcomes of GIRA-based preventative recommendations among clinicians and participants; and 3) identify correlates of adherence by condition, participant age and demographics, and social determinants of health.This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2025. This NOFO will utilize the U01 activity code.
Single Source: Outcomes of Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network - Coordinating Center (U01 Clinical Trial Required)
Open
National Institutes of Health
Health
Cooperative Agreement
Public and State controlled institutions of higher education
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Others
2025-06-06