Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)

Key Facts

Status: Open

Posted date: June 30, 2025

Opportunity ID: 359695

Opportunity number: FOR-AR-26-010

Opportunity category: Discretionary

Agency name: National Institutes of Health

Agency code: HHS-NIH11

Award floor: $0

Award ceiling: $0

Cost sharing required: No

Funding Instrument Types
  • Grant
Category of Funding Activity
  • Health
Eligible Applicants
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • State governments
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_nih11
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:state_governments
  • funding_instrument_type:grant
  • opportunity_category:discretionary
  • status:open
Description

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) together with the National Institute of Allergy and Infectious Diseases (NIAID) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications aimed at elucidating the pathological mechanisms underlying skin injury caused by toxic chemicals identified by the U.S. Department of Homeland Security as high-consequence public health threats. This initiative will emphasize the understanding of commonalities in the fundamental mechanisms of skin injuries caused by vesicants such as sulfur mustard, Lewisite, nitrogen mustard, phosgene oxime, arsenicals, and other toxic chemicals. Responsive applications will investigate the molecular and cellular pathology of at least two chemicals, belonging to different toxidromes (contact PO for more information). It is hoped that the knowledge gained will ultimately lead to the discovery and characterization of potential shared therapeutic targets in injuries caused by different chemicals, and the development of broad-spectrum medical countermeasures (MCM). This effort is part of a NIH-wide initiative to develop MCM to treat patients in mass casualty events after acute exposure to toxic chemicals as part of the Chemical Countermeasure Research Program (CCRP). Chemical Countermeasures Research Program NIAID: National Institute of Allergy and Infectious Diseases. Applications are not being solicited currently. Notice is provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise and insights into this cutaneous wound healing area are encouraged to consider applying for this new NOFO. In addition, team science approaches will be encouraged.

Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) together with the National Institute of Allergy and Infectious Diseases (NIAID) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications aimed at elucidating the pathological mechanisms underlying skin injury caused by toxic chemicals identified by the U.S. Department of Homeland Security as high-consequence public health threats. This initiative will emphasize the understanding of commonalities in the fundamental mechanisms of skin injuries caused by vesicants such as sulfur mustard, Lewisite, nitrogen mustard, phosgene oxime, arsenicals, and other toxic chemicals. Responsive applications will investigate the molecular and cellular pathology of at least two chemicals, belonging to different toxidromes (contact PO for more information). It is hoped that the knowledge gained will ultimately lead to the discovery and characterization of potential shared therapeutic targets in injuries caused by different chemicals, and the development of broad-spectrum medical countermeasures (MCM). This effort is part of a NIH-wide initiative to develop MCM to treat patients in mass casualty events after acute exposure to toxic chemicals as part of the Chemical Countermeasure Research Program (CCRP). Chemical Countermeasures Research Program NIAID: National Institute of Allergy and Infectious Diseases. Applications are not being solicited currently. Notice is provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise and insights into this cutaneous wound healing area are encouraged to consider applying for this new NOFO. In addition, team science approaches will be encouraged.
Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)
Open
National Institutes of Health
Health
Grant
State governments
County governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
2025-06-30