Sustaining HIV and TB epidemic control in Lesotho through health system strengthening and technical assistance under the President's Emergency Plan for AIDS Relief (PEPFAR)

Key Facts

Status: Open

Posted date: October 1, 2025

Archive date: March 19, 2026

Opportunity ID: 360715

Opportunity number: CDC-RFA-JG-26-0151

Opportunity category: Discretionary

Agency name: Centers for Disease Control-GHC

Agency code: HHS-CDC-GHC

Award floor: $0

Award ceiling: $0

Cost sharing required: No

Funding Instrument Types
  • Cooperative Agreement
Category of Funding Activity
  • Health
Eligible Applicants
  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
  • Unrestricted
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_cdc_ghc
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:city_or_township_governments
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:nonprofits_that_do_not_have_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:special_district_governments
  • eligible_applicants:state_governments
  • eligible_applicants:unrestricted
  • funding_instrument_type:cooperative_agreement
  • opportunity_category:discretionary
  • status:open
Description

The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $15,000,000 for Year 1, subject to the availability of funds.The goal of this NOFO is to accelerate and sustain HIV epidemic control and reduce TB incidence by attaining and sustaining the UNAIDS 95-95-95 targets through implementing interventions that address unmet needs across the clinical cascade in the four districts of Leribe, Berea, Quthing and Qacha’s Nek. To ensure sustainability, you will be expected to work with the Ministry of Health, to provide evidence-based interventions and innovative strategies, strengthen the capacity of the district health management teams, health facilities and communities to improve person-centered health service delivery. Activities include health system strengthening and continuous quality improvement in multiple areas. Provision of technical assistance in multiple areas including HIV and TB case finding; HIV care and treatment including advanced HIV disease management and cervical cancer screening, biomedical prevention including elimination of mother to child HIV transmission, pre-exposure prophylaxis; TB prevention, diagnosis, and treatment, integration of non-communicable diseases management into HIV service delivery; interface with laboratory systems; surveillance (including Recency testing) and data utilization for program improvement. The overall NOFO goal aligns with the PEPFAR 2030 strategic direction to eliminate the HIV/AIDS pandemic as a public health threat while sustainably strengthening the public health system.

Sustaining HIV and TB epidemic control in Lesotho through health system strengthening and technical assistance under the President's Emergency Plan for AIDS Relief (PEPFAR)
The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $15,000,000 for Year 1, subject to the availability of funds.The goal of this NOFO is to accelerate and sustain HIV epidemic control and reduce TB incidence by attaining and sustaining the UNAIDS 95-95-95 targets through implementing interventions that address unmet needs across the clinical cascade in the four districts of Leribe, Berea, Quthing and Qacha’s Nek. To ensure sustainability, you will be expected to work with the Ministry of Health, to provide evidence-based interventions and innovative strategies, strengthen the capacity of the district health management teams, health facilities and communities to improve person-centered health service delivery. Activities include health system strengthening and continuous quality improvement in multiple areas. Provision of technical assistance in multiple areas including HIV and TB case finding; HIV care and treatment including advanced HIV disease management and cervical cancer screening, biomedical prevention including elimination of mother to child HIV transmission, pre-exposure prophylaxis; TB prevention, diagnosis, and treatment, integration of non-communicable diseases management into HIV service delivery; interface with laboratory systems; surveillance (including Recency testing) and data utilization for program improvement. The overall NOFO goal aligns with the PEPFAR 2030 strategic direction to eliminate the HIV/AIDS pandemic as a public health threat while sustainably strengthening the public health system.
Sustaining HIV and TB epidemic control in Lesotho through health system strengthening and technical assistance under the President's Emergency Plan for AIDS Relief (PEPFAR)
Open
Centers for Disease Control-GHC
Health
Cooperative Agreement
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
Unrestricted
2025-10-01