Supporting life-saving HIV services and related health systems in Zambia on a pathway to self-reliance under the President’s Plan for AIDS Relief (PEPFAR)

Key Facts

Status: Open

Posted date: October 16, 2025

Archive date: March 19, 2026

Opportunity ID: 360760

Opportunity number: CDC-RFA-JG-26-0179

Opportunity category: Discretionary

Agency name: Centers for Disease Control-GHC

Agency code: HHS-CDC-GHC

Award floor: $0

Award ceiling: $0

Cost sharing required: No

Funding Instrument Types
  • Cooperative Agreement
Category of Funding Activity
  • Health
Eligible Applicants
  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
  • Unrestricted
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_cdc_ghc
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:city_or_township_governments
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:nonprofits_that_do_not_have_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:special_district_governments
  • eligible_applicants:state_governments
  • eligible_applicants:unrestricted
  • funding_instrument_type:cooperative_agreement
  • opportunity_category:discretionary
  • status:open
Description

The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $120,000,000 or Year 1, subject to the availability of funds.This Notice of Funding Opportunity (NOFO) will provide support for life-saving services for HIV and related health conditions in Zambia, in cooperation with the Ministry of Health (MOH) and aligned with PEPFAR’s goal of transition to host government self-reliance. You will also support the health systems necessary to ensure critical services are maintained, monitored, and implemented in a cost-effective and sustainable manner. Activities within the NOFO will provide support to the host government at the provincial, district, facility, and/or community levels to oversee, monitor, and implement evidence-based activities. Clinical support for HIV will focus on treatment, laboratory, adherence support, and retention in care. Health systems support will focus on sustainability and host government self-reliance, maintaining patient and program monitoring systems, and human resources for health.

Supporting life-saving HIV services and related health systems in Zambia on a pathway to self-reliance under the President’s Plan for AIDS Relief (PEPFAR)
The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $120,000,000 or Year 1, subject to the availability of funds.This Notice of Funding Opportunity (NOFO) will provide support for life-saving services for HIV and related health conditions in Zambia, in cooperation with the Ministry of Health (MOH) and aligned with PEPFAR’s goal of transition to host government self-reliance. You will also support the health systems necessary to ensure critical services are maintained, monitored, and implemented in a cost-effective and sustainable manner. Activities within the NOFO will provide support to the host government at the provincial, district, facility, and/or community levels to oversee, monitor, and implement evidence-based activities. Clinical support for HIV will focus on treatment, laboratory, adherence support, and retention in care. Health systems support will focus on sustainability and host government self-reliance, maintaining patient and program monitoring systems, and human resources for health.
Supporting life-saving HIV services and related health systems in Zambia on a pathway to self-reliance under the President’s Plan for AIDS Relief (PEPFAR)
Open
Centers for Disease Control-GHC
Health
Cooperative Agreement
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
Unrestricted
2025-10-16