NIH Specialized Center Grant (Parent P50)

Key Facts

Status: Open

Posted date: April 7, 2026

Opportunity ID: 361769

Opportunity number: PA-28-011

Opportunity category: Discretionary

Agency name: National Institutes of Health

Agency code: HHS-NIH11

Award floor: $0

Award ceiling: $0

Cost sharing required: No

Funding Instrument Types
  • Grant
Category of Funding Activity
  • Health
Eligible Applicants
  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_nih11
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:city_or_township_governments
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:nonprofits_that_do_not_have_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:others
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:special_district_governments
  • eligible_applicants:state_governments
  • funding_instrument_type:grant
  • opportunity_category:discretionary
  • status:open
Description

Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) encourage pursuit of the NIH’s mission through the submission of investigator-initiated Specialized Center (P50) applications. With this Parent P50 NOFO, the NIH ICOs intend to support a broadly based, multidisciplinary, often long-term research program with a specific major scientific objective or theme. The proposed Specialized Center must be related to the programmatic interests of one or more of the participating ICOs based on their scientific missions. Applications submitted in response to this NOFO are required to include one administrative core, research projects, and at least one resource core. Inclusion of a Pilot Projects core is optional. The research projects included within the Specialized Center must share a common central scientific theme, focus, and/or an overall objective. Emphasis on how the component research projects build on one another to achieve goals beyond the scope of each individual project is also expected. Specialized Center must demonstrate synergy through cohesiveness, shared resources, and collaborative impact. Statutory authority: Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

NIH Specialized Center Grant (Parent P50)
Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) encourage pursuit of the NIH’s mission through the submission of investigator-initiated Specialized Center (P50) applications. With this Parent P50 NOFO, the NIH ICOs intend to support a broadly based, multidisciplinary, often long-term research program with a specific major scientific objective or theme. The proposed Specialized Center must be related to the programmatic interests of one or more of the participating ICOs based on their scientific missions. Applications submitted in response to this NOFO are required to include one administrative core, research projects, and at least one resource core. Inclusion of a Pilot Projects core is optional. The research projects included within the Specialized Center must share a common central scientific theme, focus, and/or an overall objective. Emphasis on how the component research projects build on one another to achieve goals beyond the scope of each individual project is also expected. Specialized Center must demonstrate synergy through cohesiveness, shared resources, and collaborative impact. Statutory authority: Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
NIH Specialized Center Grant (Parent P50)
Open
National Institutes of Health
Health
Grant
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
Others
2026-04-07