Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed)

Key Facts

Status: Open

Posted date: May 6, 2026

Opportunity ID: 362278

Opportunity number: PAR-27-029

Opportunity category: Discretionary

Agency name: National Institutes of Health

Agency code: HHS-NIH11

Award floor: $960,898

Award ceiling: $1,008,943

Cost sharing required: No

Funding Instrument Types
  • Cooperative Agreement
Category of Funding Activity
  • Health
Eligible Applicants
  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_nih11
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:city_or_township_governments
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:nonprofits_that_do_not_have_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:others
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:special_district_governments
  • eligible_applicants:state_governments
  • funding_instrument_type:cooperative_agreement
  • opportunity_category:discretionary
  • status:open
Description

This Notice of Funding Opportunity (NOFO) encourages applications to provide continuing support for a National Swine Resource and Research Center (NSRRC). The NSRRC aims to enable gold-standard science in biomedical research by serving as a centralized national resource for the creation, breeding, cryopreservation, and distribution of genetically modified models. By consolidating these essential functions, the NSRRC significantly reduces variability and improves reproducibility across studies, ensuring that researchers have access to consistent, high-quality, specific pathogen-free models. Centralizing the resource also eliminates redundancy and high costs associated with individual laboratories maintaining separate facilities and breeding programs for these models, allowing investigators to focus their efforts on research rather than infrastructure. Additionally, the NSRRC provides genotyping and phenotyping services, infectious disease monitoring, and protocol distribution to facilitate their use for biomedical research. The Center also serves as a source of information and training related to the care and use of these models in biomedical research to study human health and disease and suitability of a model’s faithful representation of the biological system(s) proposed to be studied. The Center serves as a resource to lead the development of alternative or complementary approaches available, including new approach methodologies (NAMs), alongside in vivo models.

Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed)
This Notice of Funding Opportunity (NOFO) encourages applications to provide continuing support for a National Swine Resource and Research Center (NSRRC). The NSRRC aims to enable gold-standard science in biomedical research by serving as a centralized national resource for the creation, breeding, cryopreservation, and distribution of genetically modified models. By consolidating these essential functions, the NSRRC significantly reduces variability and improves reproducibility across studies, ensuring that researchers have access to consistent, high-quality, specific pathogen-free models. Centralizing the resource also eliminates redundancy and high costs associated with individual laboratories maintaining separate facilities and breeding programs for these models, allowing investigators to focus their efforts on research rather than infrastructure. Additionally, the NSRRC provides genotyping and phenotyping services, infectious disease monitoring, and protocol distribution to facilitate their use for biomedical research. The Center also serves as a source of information and training related to the care and use of these models in biomedical research to study human health and disease and suitability of a model’s faithful representation of the biological system(s) proposed to be studied. The Center serves as a resource to lead the development of alternative or complementary approaches available, including new approach methodologies (NAMs), alongside in vivo models.
Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed)
Open
National Institutes of Health
Health
Cooperative Agreement
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
Others
2026-05-06