Childhood Asthma in Urban Settings Clinical Research Network

Key Facts

Status: Open

Posted date: June 24, 2026

Opportunity ID: 362950

Opportunity number: RFA-AI-28-007

Opportunity category: Discretionary

Agency name: National Institutes of Health

Agency code: HHS-NIH11

Award floor: $0

Award ceiling: $0

Cost sharing required: No

Funding Instrument Types
  • Cooperative Agreement
Category of Funding Activity
  • Health
Eligible Applicants
  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Tools
Categories (use these for quoted searches)
  • agency_code:hhs_nih11
  • category_of_funding_activity:health
  • cost_sharing_or_matching_requirement:false
  • eligible_applicants:city_or_township_governments
  • eligible_applicants:county_governments
  • eligible_applicants:for_profit_organizations_other_than_small_businesses
  • eligible_applicants:independent_school_districts
  • eligible_applicants:native_american_tribal_governments_federally_recognized
  • eligible_applicants:native_american_tribal_organizations_other_than_federally_recognized_tribal_governments
  • eligible_applicants:nonprofits_having_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:nonprofits_that_do_not_have_a_501_c_3_status_with_the_irs_other_than_institutions_of_higher_education
  • eligible_applicants:others
  • eligible_applicants:private_institutions_of_higher_education
  • eligible_applicants:public_and_state_controlled_institutions_of_higher_education
  • eligible_applicants:public_housing_authoritiesindian_housing_authorities
  • eligible_applicants:small_businesses
  • eligible_applicants:special_district_governments
  • eligible_applicants:state_governments
  • funding_instrument_type:cooperative_agreement
  • opportunity_category:discretionary
  • status:open
Description

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) network. The CAUSE network will support multi-site clinical studies and trials on the prevention and treatment of asthma in economically disadvantaged pediatric populations where disease burden is high. The objectives of the CAUSE network are to develop and test innovative hypotheses and strategies for asthma prevention; identify/test new treatment targets (including targets for intervention based on mechanisms of type 2 low asthma); and continue to explore the risk relationship between upper and lower airway. Using systems biology approaches, CAUSE will continue to identify disease endotypes that may be suitable targets for existing and novel therapeutic modalities. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Childhood Asthma in Urban Settings Clinical Research Network
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) network. The CAUSE network will support multi-site clinical studies and trials on the prevention and treatment of asthma in economically disadvantaged pediatric populations where disease burden is high. The objectives of the CAUSE network are to develop and test innovative hypotheses and strategies for asthma prevention; identify/test new treatment targets (including targets for intervention based on mechanisms of type 2 low asthma); and continue to explore the risk relationship between upper and lower airway. Using systems biology approaches, CAUSE will continue to identify disease endotypes that may be suitable targets for existing and novel therapeutic modalities. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Childhood Asthma in Urban Settings Clinical Research Network
Open
National Institutes of Health
Health
Cooperative Agreement
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
Others
2026-06-24